# Equally contributed first authors
* Corresponding author(s)

Structural basis of transcription-coupled H3K36 trimethylation by Set2 in coordination with FACT
Tomoya Kujirai#, Haruhiko Ehara#, Tomoko Ito, Masami Henmi, Eriko Oya, Takehiko Kobayashi, Shun-Ichi Sekine*, Hitoshi Kurumizaka*
Science Advances 86, 78-96 (2026)

Hypoxia-induced ribosomal RNA modifications in the peptidyl-transferase center contribute to anaerobic growth of bacteria
Kensuke Ishiguro, Karin Midorikawa, Naoki Shigi, Satoshi Kimura, Aivar Liiv, Takeshi Yokoyama, Takuhiro Ito, Mikako Shirouzu, Jaanus Remme, Kenjyo Miyauchi, Tsutomu Suzuki*
Molecular Cell 86, 78-96 (2026)

Structural analysis of a symbiotic system involving a Nanobdellati archaeon by cryo-electron tomography
Sakurako Goto-Ito, Shingo Kato, Mari Takahashi, Ayako Sakamoto, Atsushi Yamagata, Yongchan Lee, Haruhiko Ehara, Mayuko Sato, Kiminori Toyooka, Moriya Ohkuma, Takuhiro Ito*
The Journal of Biochemistry 179, 21-30 (2026)

Structural Insights into the Role of eIF3 in Translation Mediated by the HCV IRES
Wakana Iwasaki, Kazuhiro Kashiwagi, Ayako Sakamoto, Madoka Nishimoto, Mari Takahashi, Kodai Machida, Hiroaki Imataka, Akinobu Matsumoto, Yuichi Shichino, Shintaro Iwasaki, Koshi Imami, and Takuhiro Ito*
Proceedings of the National Academy of Sciences, e2505538122 (2025)

Structural basis for E3 ubiquitin ligase UHRF1 binding to nucleosome core particle and histone H3 ubiquitination
Reia Shikimachi, Shun Matsuzawa, Hiroki Onoda, Tsuyoshi Konuma, Atsushi Yamagata, Mikako Shirouzu, Kosuke Yamaguchi, Kyohei Arita*
Journal of Biological Chemistory 301, 110894 (2025)

Conformational alteration of DOCK5•ELMO1 signalosome on lipid membrane
Takehiro Shinoda, Kazushige Katsura, Yoshiko Ishizuka-Katsura, Kazuharu Hanada, Mayumi Yonemochi, Yuki Miyamoto, Mutsuko Kukimoto-Niino, Junji Yamauchi, Mikako Shirouzu*
Communications Biology 8, 1523 (2025)

Cryo-EM reveals evolutionarily conserved and distinct structural features of plant CG maintenance methyltransferase MET1
Amika Kikuchi, Atsuya Nishiyama, Yoshie Chiba, Makoto Nakanishi, Taiko Kim To, Kyohei Arita*
Nature Communiations 16, 8524 (2025)

Monoclonal antibodies against human TMPRSS2 prevent infection by any SARS-CoV-2 variant
Michishige Harada, Takehisa Matsumoto, Mizuki Yamamoto, Jin Goda, Akiko Idei, Kenichi Ohtaki, Natsuki Kojima, Natsumi Yoneda, Kosuke Miyauchi, Kazushige Katsura, Mariko Ikeda, Kazuharu Hanada, Yoshiko Ishizuka-Katsura, Toshiaki Hosaka, Tamao Hisano, Toshie Kaizuka, Takako Yamamoto, Masashi Matsuda, Manabu Nakayama, Akiko Sugimoto-Ishige, Machie Sakuma, Rina Hashimoto, Kazuo Takayama, Misako Nakayama, Cong Thanh Nguyen, Hirohito Ishigaki, Yasushi Itoh, Yoshinobu Hashizume,
Minoru Yoshida,Yasushi Kawaguchi, Makoto Takeda, Haruhiko Koseki, Mikako Shirouzu, Jun-ichiro Inoue, and Takashi Saito*
iScience 28, 113424 (2025)

Carotenoids bind rhodopsins and act as photocycle-accelerating pigments in marine Bacteroidota
Takayoshi Fujiwara#, Toshiaki Hosaka#, Masumi Hasegawa-Takano, Yosuke Nishimura, Kento Tominaga, Kaho Mori, Satoshi Nishino, Yuno Takahashi, Tomomi Uchikubo-Kamo, Kazuharu Hanada, Takashi Maoka, Shinichi Takaichi, Keiichi Inoue*, Mikako Shirouzu* & Susumu Yoshizawa*
Nature Microbiology 10, 2603-2615 (2025)

Structures of USP7 in active and inactive states bound to DNMT1 revealed by cryo-EM
Nao Nakamura#, Sae Yoshimi#, Amika Kikuchi, Hiroki Onoda, Satomi Kori, Makoto Nakanishi, Atsuya Nishiyama, Kyohei Arita*
Structure 33, 1510-1518 (2025)

Structural insights into tRNA recognition of the human FTSJ1-THADA complex
Kensuke Ishiguro, Atsushi Fujimura & Mikako Shirouzu*
Communications Biology 8, 893 (2025)

Structural basis of urate transport by glucose transporter 9
Daiki Matsushita#, Yu Toyoda#, Yongchan Lee, Maeda Aoi, Hirotaka Matsuo, Tappei Takada, Tomohiro Nishizawa*
Cell Reports 44, 115514 (2025)

Membrane structure-responsive lipid scrambling by TMEM63B to control plasma membrane lipid distribution
Yugo Miyata#, Katsuya Takahashi#, Yongchan Lee, Cheryl S. Sultan, Risa Kuribayashi, Masatomo Takahashi, Kosuke Hata, Takeshi Bamba, Yoshihiro Izumi, Kehong Liu, Tomoko Uemura, Norimichi Nomura, So Iwata, Shigekazu Nagata, Tomohiro Nishizawa* & Katsumori Segawa*
Nature Structual & Molecular Biology 32, 185–198 (2025)

Structural insights into promoter-proximal pausing of RNA polymerase II at +1 nucleosome
Masahiro Naganuma#, Tomoya Kujirai#, Haruhiko Ehara#, Tamami Uejima, Tomoko Ito, Mie Goto, Mari Aoki, Masami Henmi, Sayako Miyamoto-Kohno, Mikako Shirouzu, Hitoshi Kurumizaka*, and Shun-ichi Sekine*
Science Advances 11, eadu0577 (2025)